Utilization of endogenous fatty acid stores for energy production in bovine preimplantation embryos.

@article{SuttonMcDowall2012UtilizationOE,
  title={Utilization of endogenous fatty acid stores for energy production in bovine preimplantation embryos.},
  author={Melanie L. Sutton-McDowall and Deanne Kate Feil and Rebecca L Robker and Jeremy G. Thompson and Kylie Renee Dunning},
  journal={Theriogenology},
  year={2012},
  volume={77 8},
  pages={1632-41}
}
Although current embryo culture media are based on carbohydrate metabolism of embryos, little is known about metabolism of endogenous lipids. L-carnitine is a β-oxidation cofactor absent in most culture media. The objective was to investigate the influence of L-carnitine supplementation on bovine embryo development. Abattoir-derived bovine cumulus oocyte complexes were cultured and fertilized. Post-fertilization, presumptive zygotes were transferred into a basic cleavage medium ± carbohydrates… CONTINUE READING
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