Utilization of Mercaptoethylgluconamide for Depleting Human Cystinotic Fibroblasts of their Accumulated Lysosomal Cystine

Abstract

ABSTRACT: Human cystinotic fibroblasts were completely depleted of their accumulated intracellular free cystine within a 2-h time interval when exposed to culture medium containing between 1 and 5 mM mercaptoethylgluconamide. This cystine-depleting action of mercaptoethylgluconamide was observed with three different human cystinotic fibroblast cell lines… (More)
DOI: 10.1203/00006450-198907000-00020

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@article{Pisoni1989UtilizationOM, title={Utilization of Mercaptoethylgluconamide for Depleting Human Cystinotic Fibroblasts of their Accumulated Lysosomal Cystine}, author={Ronald L. Pisoni and Karen M Lisowski and Rosemary M Lemons and Jess G. Thoene}, journal={Pediatric Research}, year={1989}, volume={26}, pages={73-76} }