Utility of unenhanced fat-suppressed T1-weighted MRI in children with sickle cell disease — can it differentiate bone infarcts from acute osteomyelitis?

@article{Delgado2015UtilityOU,
  title={Utility of unenhanced fat-suppressed T1-weighted MRI in children with sickle cell disease — can it differentiate bone infarcts from acute osteomyelitis?},
  author={Jorge Delgado and Maria A. Bedoya and Abby M. Green and Diego Jaramillo and Victor M. Ho-Fung},
  journal={Pediatric Radiology},
  year={2015},
  volume={45},
  pages={1981-1987}
}
BackgroundChildren with sickle cell disease (SCD) are at risk of bone infarcts and acute osteomyelitis. [] Key MethodObjectiveTo evaluate the reliability of unenhanced T1-W fat-saturated MRI for differentiation between bone infarcts and acute osteomyelitis in children with SCD.Materials and methodsWe retrospectively reviewed the records of 31 children (20 boys, 11 girls; mean age 10.6 years, range 1.1–17.9 years) with SCD and acute bone pain who underwent MR imaging including unenhanced T1-W fat-saturated…
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15 Citations
Background Citations
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15 Citations

T2-blackout effect on DWI as a sign of early bone infarct and sequestration in a patient with sickle cell disease.
Chronic Osteomyelitis of Long Bones: Imaging Pearls and Pitfalls in Pediatrics.
TLDR
The epidemiologic, clinical, and histopathologic features of chronic bacterial osteomyelitis are reviewed and radiologist familiarity with imaging findings and mimickers is essential.
Hematological and Circulatory Bone Lesions: Imaging Pitfalls
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MRI findings of normal bone marrow from birth to elderly are addressed, along with the normal variants that may be diagnostic pitfalls, addressing the imaging pitfalls and how to avoid them.
ACR Appropriateness Criteria® Osteomyelitis or Septic Arthritis-Child (Excluding Axial Skeleton).
EVALUATION OF SERUM PROCALCITONIN LEVELS AS A DIAGNOSTIC MARKER OF EARLY INFECTION IN PATIENTS WITH ACUTE BONE AND JOINT INFECTION: A HOSPITAL BASED STUDY
  • Vikas Pandey
  • Medicine
    International Journal of Orthopaedics Traumatology & Surgical Sciences
  • 2019
TLDR
Procalcitonin as diagnostic tool for earliest and specific diagnosis of acute bone and joint infection was evaluated and ESR, CRP and TLC was found to be elevated in all the cases and significant correlation was observed between cases and PCT serum level.
Management of Osteomyelitis in Sickle Cell Disease: Review Article
TLDR
Treatment of osteomyelitis in patients with SCD may be medical or surgical, but considerations in antibiotic selection and management preoperatively and postoperatively must be taken to ensure optimal outcomes.
Hematogenous Osteomyelitis in Infants and Children: Imaging of a Changing Disease.
TLDR
An overview of the imaging implications directed by the changing epidemiology, the newer insights of anatomy and pathophysiology,The imaging characteristics with emphasis on specific locations and disease complications, and the differential diagnosis considerations are provided.
The Acutely Limping Preschool and School‐Age Child: An Imaging Perspective
TLDR
The ultimate goal is to familiarize the interpreting radiologist with the imaging appearance of specific clinical entities that lead to acute limp while providing a readily accessible resource on how to image the patient most appropriately and judiciously.
MRI nomenclature for musculoskeletal infection
TLDR
The committee arrived at consensus definitions for cellulitis, soft tissue abscess, and necrotizing infection, while discouraging the nonspecific term phlegmon, and recommends using terms that describe the likelihood of osteomyelitis in cases where definitive signal changes are lacking.
Characteristics and outcomes of osteomyelitis in children with sickle cell disease: A 10‐year single‐center experience
TLDR
Patients with sickle cell disease (SCD) are at increased risk for osteomyelitis (OM), and characteristics and outcomes of OM in SCD patients treated at the authors' center over 10‐year period are reported.
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