Utility of thin-layer preparations in thyroid fine-needle aspiration: diagnostic accuracy, cytomorphology, and optimal sample preparation.

@article{Frost1998UtilityOT,
  title={Utility of thin-layer preparations in thyroid fine-needle aspiration: diagnostic accuracy, cytomorphology, and optimal sample preparation.},
  author={Andra R. Frost and Mary K Sidawy and M Ferfelli and Sana O. Tabbara and N A Bronner and Keith Brosky and Mark E. Sherman},
  journal={Cancer},
  year={1998},
  volume={84 1},
  pages={17-25}
}
BACKGROUND The efficacy of preparing thyroid fine-needle aspirations (FNAs) as thin-layer slides has not been evaluated extensively. METHODS To evaluate the efficacy of thin-layer cytology, the authors examined thyroid FNAs from 135 unselected palpable lesions that were aspirated using uniform procedures and prepared as air-dried, Diff-Quik-stained direct smears (DS) and Papanicolaou-stained thin-layer slides (TL). Diagnoses rendered independently on masked slides from each thyroid nodule… CONTINUE READING

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