• Corpus ID: 2270556

Utility of serum protein-bound neutral hexoses and L-fucose for estimation of malignant tumor extension and evaluation of efficacy of therapy.

  title={Utility of serum protein-bound neutral hexoses and L-fucose for estimation of malignant tumor extension and evaluation of efficacy of therapy.},
  author={A S Evans and Melissa Dolan and Philip Z. Sobocinski and Fred A. Quinn},
  journal={Cancer research},
  volume={34 3},
Summary The method used permits correction for the influence of the neutral hexoses, galactose and mannose, on the apparent concentration of protein-bound l-fucose, as estimated by the Dische-Shettles CyR3 reaction. The values thus obtained, together with the serum concentrations of neutral hexoses, were evaluated in a series of patients, 109 of whom had confirmed diagnoses of cancer. In patients sampled prior to definitive treatment, 89.2% (74 of 83) had elevated ratios of fucose to protein… 

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