Utility of plasma circulating mRNA as a marker to detect hepatic injury.

@article{Kudo2008UtilityOP,
  title={Utility of plasma circulating mRNA as a marker to detect hepatic injury.},
  author={Yuka Kudo and Takashi Ochi and Hideaki Shimada and Shinji Ogawa and Katsuhiro Shinjo},
  journal={The Journal of veterinary medical science},
  year={2008},
  volume={70 9},
  pages={
          993-5
        }
}
Utility of plasma circulating mRNA as a molecular marker to detect hepatic injury was evaluated. Total RNA was isolated from plasma of the rat liver fibrosis models at various time points, and plasma circulating mRNAs of major liver-derived genes, albumin and haptoglobin, were measured by real-time quantitative reverse transcription polymerase chain reaction (qRT-PCR). Sensitivity and kinetics of plasma circulating mRNA were compared with those of plasma alanine aminotransferase (ALT) activity… CONTINUE READING

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