Utility of mass spectrometry for proteome analysis: part I. Conceptual and experimental approaches.

@article{Ahmed2008UtilityOM,
  title={Utility of mass spectrometry for proteome analysis: part I. Conceptual and experimental approaches.},
  author={F. ElZahraa Ahmed},
  journal={Expert review of proteomics},
  year={2008},
  volume={5 6},
  pages={
          841-64
        }
}
This article is the first in a series of reviews intended as a tutorial providing the inexperienced, as well as the experienced, reader with an overview of principles of peptide and protein fragmentation in mass spectrometers for protein identification, surveying of the different types of instrument configurations and their combinations for protein identification. The first mass spectrometer was developed in 1899, but it took almost a century for the instrument to become a routine analytical… CONTINUE READING
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