Utility of ketone measurement in the prevention, diagnosis and management of diabetic ketoacidosis

@article{Misra2015UtilityOK,
  title={Utility of ketone measurement in the prevention, diagnosis and management of diabetic ketoacidosis},
  author={Shivani Misra and Nick S. Oliver},
  journal={Diabetic Medicine},
  year={2015},
  volume={32},
  pages={14 - 23}
}
Ketone measurement is advocated for the diagnosis of diabetic ketoacidosis and assessment of its severity. Assessing the evidence base for ketone measurement in clinical practice is challenging because multiple methods are available but there is a lack of consensus about which is preferable. Evaluating the utility of ketone measurement is additionally problematic because of variability in the biochemical definition of ketoacidosis internationally and in the proposed thresholds for ketone… 
Controversies Around the Measurement of Blood Ketones to Diagnose and Manage Diabetic Ketoacidosis.
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A perspective on these topics is provided to complement current recommendations and to suggest how future research may improve its use in the DKA context.
Evaluation of the Accuracy of Capillary Hydroxybutyrate Measurement Compared with Other Measurements in the Diagnosis of Diabetic Ketoacidosis: A Systematic Review
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  • 2022
TLDR
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TLDR
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TLDR
The various ways of approaching patients who suffer from type-one diabetes during ketoacidosis and keto-acidotic coma are evaluated, to understand the triggers and pathophysiology behind this condition, and explore ways to prevent them.
Continuous Ketone Monitoring Consensus Report 2021.
TLDR
This report is intended to support the development of safe and effective continuous ketone monitoring and to apply this technology in ways that will benefit people with diabetes.
Blood versus urine ketone monitoring in a pediatric cohort of patients with type 1 diabetes: a crossover study
TLDR
Children and adolescents with T1D outside of remission phase experiencing HE tested ketones alternatively with a blood ketone meter or urine ketone test strips and gave their opinion on screening methods after completion of clinical trial, suggesting that ketone monitoring did not affect correction of glycemia.
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TLDR
Ketone body measurement is relatively inexpensive and can provide metabolic insights to help guide disease management and optimize weight loss.
Microneedle-Based Detection of Ketone Bodies along with Glucose and Lactate: Toward Real-Time Continuous ISF Monitoring of Diabetic Ketosis/Ketoacidosis.
TLDR
The first use of a real-time continuous ketone bodies monitoring (CKM) microneedle platform is presented, based on the electrochemical monitoring of β-hydroxybutyrate, as the dominant biomarker of ketone formation.
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