Utility of hyposmia and hypogeusia for the diagnosis of COVID-19

@article{Bnzit2020UtilityOH,
  title={Utility of hyposmia and hypogeusia for the diagnosis of COVID-19},
  author={François B{\'e}n{\'e}zit and Paul Le Turnier and Charles Declerck and C{\'e}cile Paill{\'e} and Matthieu Revest and Vincent Dub{\'e}e and Pierre Tattevin and C{\'e}dric Marion Jean-Marc Pauline Sol{\`e}ne Anne M{\'e}lanie Charl Arvieux Baldeyrou Chapplain Comacle Patrat-Delon M and C{\'e}dric Arvieux and Marion Baldeyrou and Jean Marc Chapplain and Pauline Comacle and Sol{\`e}ne Patrat-Delon and Anne Maillard and M{\'e}lanie Poinot and Charlotte Pronier and Faouzi Souala and Vincent Thibault and Pierre Abgueguen and Hélène Cormier and Val{\'e}rie Delbos and Marine de la Chapelle and Alexandra Ducancelle and Rafael Mahieu and Val{\'e}rie Rabier and Sami Rehaiem and Yves-Marie Vandamme and Charlotte Biron and Jean Claude Brochon and David Boutoille and Marie Chauveau and Colin Deschanvres and Benjamin Jean Gaborit and Jo{\"e}l Jenvrin and Rapha{\"e}l Lecomte and Maeva Lefebvre and François Raffi},
  journal={The Lancet. Infectious Diseases},
  year={2020},
  volume={20},
  pages={1014 - 1015}
}

Topics from this paper

Complications and Pathophysiology of COVID-19 in the Nervous System
TLDR
The complications and potential mechanisms of COVID-19 in the nervous system in this review have been discussed to provide some reference for designing optimal therapeutic strategies. Expand
The COVID-19 pandemic: catching up with the cataclysm
TLDR
A picture of SARS-CoV-2 epidemiological characteristics, the clinical symptoms experienced by patients of varying age groups, the molecular virology of SSE, and the treatment regimens currently employed for fighting SSE infection are provided as well as their outcomes. Expand
The COVID-19 pandemic: catching up with the cataclysm
Infection caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which belongs to the Coronaviridae family and is a positive-sense single-stranded RNA virus originating from Wuhan,Expand
Neurological associations of COVID-19
TLDR
The COVID-19 pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is of a scale not seen since the 1918 influenza pandemic and the proportion of infections leading to neurological disease will probably remain small. Expand
Neurological Associations of COVID-19
TLDR
The COVID-19 pandemic, caused by SARS-CoV-2, is of a scale not seen since the 1918 influenza pandemic and so much of the population infected, the overall number of neurological patients, and their associated health, social and economic costs, may be large. Expand
The involvement of the central nervous system in patients with COVID-19
TLDR
The current evidence for CNS involvement in COVID-19 is discussed and it is highlighted that the high pathogenicity of SARS-CoV-2 might be due to its neuroinvasive potential. Expand
Olfactory and Taste Dysfunction in Patients with Asymptomatic and Mildly Symptomatic COVID-19 in Korea
TLDR
It is imperative to identify the distinctive clinical features of COVID-19 to guide strategic testing approaches for the early diagnosis and prevention of disease. Expand
Covid-19 in outpatients—Is fever a useful indicator for SARS-CoV-2 infection?
TLDR
Fever seems to be less common in patients of relatively young age diagnosed with mild to moderate Covid-19, suggesting that body temperature alone may be an insufficient indicator of SARS-CoV-2 infection. Expand
Olfactory dysfunction in the COVID-19 outbreak.
TLDR
To date, the literature is widely heterogeneous regarding the loss of smell; therefore, home isolation measures and/or social distancing are advised, and diagnostic tests for SARS-CoV-2 when possible in those patients with sudden and severe loss of sense who cannot be promptly evaluated. Expand
Post-Acute COVID-19 Neurological Syndrome: A New Medical Challenge
TLDR
There is consensus on the need to define which symptoms persist after the infection and which disabilities may arise after COVID-19, and the psychological impact of the pandemic should not be underestimated, although there is currently no definition for this condition. Expand
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 13 REFERENCES
Clinical Characteristics of Coronavirus Disease 2019 in China
TLDR
During the first 2 months of the current outbreak, Covid-19 spread rapidly throughout China and caused varying degrees of illness, and patients often presented without fever, and many did not have abnormal radiologic findings. Expand
The neuroinvasive potential of SARS‐CoV2 may play a role in the respiratory failure of COVID‐19 patients
TLDR
It remains to make clear whether the potential invasion of SARS‐CoV2 is partially responsible for the acute respiratory failure of patients with COVID‐19, which emerged in December 2019 in Wuhan, China and rapidly spreads around the world. Expand
Neurological Manifestations of Hospitalized Patients with COVID-19 in Wuhan, China: a retrospective case series study
TLDR
Compared with non-severe patients with COVID-19, severe patients commonly had neurologic symptoms manifested as acute cerebrovascular diseases, consciousness impairment and skeletal muscle symptoms. Expand
Detection of SARS-CoV-2 in Different Types of Clinical Specimens.
This study describes results of PCR and viral RNA testing for SARS-CoV-2 in bronchoalveolar fluid, sputum, feces, blood, and urine specimens from patients with COVID-19 infection in China to identifyExpand
Interferon-Mediated Immunopathological Events Are Associated with Atypical Innate and Adaptive Immune Responses in Patients with Severe Acute Respiratory Syndrome
TLDR
It is argued that unregulated IFN responses during acute-phase SARS may culminate in a malfunction of the switch from innate immunity to adaptive immunity, and the potential for the use of the gene signatures described in this study to better assess the immunopathology and clinical management of severe viral infections. Expand
IFN-I response timing relative to virus replication determines MERS coronavirus infection outcomes.
TLDR
It is suggested that the relative timing of the IFN-I response and maximal virus replication is key in determining outcomes, at least in infected mice, and IFn-αβ or combination therapy may need to be used cautiously to treat viral infections in clinical settings. Expand
Baricitinib as potential treatment for 2019-nCoV acute respiratory disease
TLDR
It is suggested that baricitinib could be trialled, using an appropriate patient population with 2019-nCoV acute respiratory disease, to reduce both the viral entry and the inflammation in patients, using endpoints such as the MuLBSTA score, an early warning model for predicting mortality in viral pneumonia. Expand
Taste and smell losses in HIV infected patients
TLDR
Overall the results suggest abnormalities in the peripheral and central nervous systems, and subjective distortion of taste and smell in HIV infected subjects which may be of clinical significance in the development or progression of HIV associated wasting. Expand
Gustatory dysfunction after mandibular zoster
TLDR
In two cases of patients suffering from mandibular zoster associated with subjective taste disorder, gustatory measures confirmed ipsilateral hemiageusia of the anterior two-thirds of the tongue, and taste function seems to recover quickly. Expand
The neuroinvasive potential of SARS-CoV2 may be at least partially responsible for the respiratory failure of COVID-19 patients
  • J Med Virol
  • 2020
...
1
2
...