Utility of cytokeratin immunostaining in separating pulmonary adenocarcinomas from colonic adenocarcinomas.

@article{Loy1994UtilityOC,
  title={Utility of cytokeratin immunostaining in separating pulmonary adenocarcinomas from colonic adenocarcinomas.},
  author={Timothy S Loy and Robert Calaluce},
  journal={American journal of clinical pathology},
  year={1994},
  volume={102 6},
  pages={764-7}
}
Adenocarcinomas of uncertain origin are a frequent problem for surgical pathologists. To determine the utility of immunostaining for cytokeratin 7 and cytokeratin 20 in the separation of pulmonary adenocarcinomas from colonic adenocarcinomas, we studied routinely processed, formalin-fixed tissue from 151 of these tumors using commercially available monoclonal antibodies and an avidin-biotin immunohistochemical technique. Used alone, neither cytokeratin 7 immunostaining or cytokeratin 20… CONTINUE READING

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