Utility of adenoviral-mediated Fas ligand gene transfer to modulate islet allograft survival.

Abstract

BACKGROUND One of the best-defined mechanisms for the induction of apoptosis involves signaling via the cell surface molecule Fas, after binding of Fas ligand. Expression of Fas ligand is tightly regulated, being expressed primarily by T cells after activation, where it serves as a self-regulatory mechanism for immune responses. Fas ligand has also been… (More)

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@article{Judge1998UtilityOA, title={Utility of adenoviral-mediated Fas ligand gene transfer to modulate islet allograft survival.}, author={Tom Judge and N. M. Desai and Z. Yang and Sima Rostami and Laura Alonso and H Zhang and Yongmei Chen and James F Markman and Ronald DeMateo and C. F. Barker and A. Naji and Laurence A. Turka}, journal={Transplantation}, year={1998}, volume={66 4}, pages={426-34} }