Utility of a dual immunostain cocktail comprising of p53 and CK20 to aid in the diagnosis of non-neoplastic and neoplastic bladder biopsies

Abstract

BACKGROUND Distinction between non-neoplastic and neoplastic bladder lesions is therapeutically and prognostically important. Our objective is to describe the use of double immunohistochemistry (DIHC) for p53+CK20 as a tool for diagnosing neoplasia in bladder biopsies. METHODS p53+CK20 DIHC were examined in 38 reactive atypia, 10 dysplasia, 9 carcinoma in… (More)
DOI: 10.1186/1746-1596-4-35

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