Utility of a CEA, CD15, calretinin, and CK5/6 panel for distinguishing between mesotheliomas and pulmonary adenocarcinomas in clinical practice.

@article{Mohammad2012UtilityOA,
  title={Utility of a CEA, CD15, calretinin, and CK5/6 panel for distinguishing between mesotheliomas and pulmonary adenocarcinomas in clinical practice.},
  author={Tareq Mohammad and John Garratt and Emina Emilia Torlakovic and Blake C. Gilks and Andrew Churg},
  journal={The American journal of surgical pathology},
  year={2012},
  volume={36 10},
  pages={1503-8}
}
Most reports on antibodies that claimed to separate mesothelioma from pulmonary adenocarcinoma originated from academic centers or specialized immunohistochemistry laboratories, but little is known about how such stains perform in general practice laboratories. The Canadian Immunohistochemistry Quality Control program circulates tissue array slides to laboratories across Canada; these are stained and then interpreted by the local laboratory and by a set of experienced reviewers. For Canadian… CONTINUE READING
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