Corpus ID: 18918156

Utility of PCR in diagnosis of problematic cases of typhoid.

  title={Utility of PCR in diagnosis of problematic cases of typhoid.},
  author={Abdul Haque and Nadia Ahmed and Arslan Masood Peerzada and Ahmad Raza and Saima Bashir and Gawahir Abbas},
  journal={Japanese journal of infectious diseases},
  volume={54 6},
Typhoid is a global problem. Conventional diagnostic methods have limitations. The Widal test gives a high proportion of false positive results, and indiscriminate use of antibiotics has reduced the utility of blood culture. Consequently, these procedures are inadequate for diagnosing suspected cases of typhoid that do not present clear-cut symptoms. We previously showed that PCR-based diagnosis of typhoid targeting the flagellin gene has unparalleled specificity. We assessed the utility of… Expand

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