Utility of CDX-2 in distinguishing between primary and secondary (intestinal) mucinous ovarian carcinoma: an immunohistochemical comparison of 43 cases.

@article{Raspollini2004UtilityOC,
  title={Utility of CDX-2 in distinguishing between primary and secondary (intestinal) mucinous ovarian carcinoma: an immunohistochemical comparison of 43 cases.},
  author={Maria Rosaria Raspollini and Gianni Amunni and Alessandro Villanucci and G Svegliati- Baroni and Antonio Taddei and Gian Luigi Taddei},
  journal={Applied immunohistochemistry & molecular morphology : AIMM},
  year={2004},
  volume={12 2},
  pages={127-31}
}
Primary and secondary mucinous tumors can involve the ovaries and have similar histologic appearances. The differential diagnosis is important for surgical and chemotherapeutic treatment and for the prognosis, but often it is extremely difficult. This article discusses an immunohistochemical panel that includes carcinoembryonic antigen (CEA), cytokeratin (CK) 7, CK20, CA125, CA19.9, and a new marker, CDX-2, for the distinction between primary ovarian mucinous carcinomas and metastatic… CONTINUE READING

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