Utility of Acetylcysteine in Treating Poisonings and Adverse Drug Reactions

@article{Chyka2000UtilityOA,
  title={Utility of Acetylcysteine in Treating Poisonings and Adverse Drug Reactions},
  author={Peter A. Chyka and A Y Butler and Billie J. Holliman and M. I. Herman},
  journal={Drug Safety},
  year={2000},
  volume={22},
  pages={123-148}
}
As recognition of the role of free radicals and reactive toxins in the pathogenesis of disease, poisoning, and adverse drug reactions has evolved, interest in the use of acetylcysteine as a modulator of these effects has steadily increased in recent years. Acetylcysteine is commonly thought to serve as a glutathione precursor and consequently can increase or sustain intracellular glutathione which scavenges reactive oxygen species caused by toxins or subsequent tissue injury. At least 10… Expand
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