Utilità della citofluorimetria a flusso su liquido da BAL nella diagnosi di Istiocitosi a cellule di Langerhans (ICL)

  title={Utilit{\`a} della citofluorimetria a flusso su liquido da BAL nella diagnosi di Istiocitosi a cellule di Langerhans (ICL)},
  author={Vincenzo Brescia and Salvatore Scolozzi and Marta Zizzari and Chiara Zecca and Maria Teresa Dell’Abate and Marco Mazzotta},
  journal={La Rivista Italiana della Medicina di Laboratorio - Italian Journal of Laboratory Medicine},
Le malattie polmonari interstiziali costituiscono un gruppo eterogeneo di malattie del parenchima polmonare a varia eziologia, presentazione clinica e radiografica, caratteristiche istopatologiche e decorso clinico. Sono state proposte diverse classificazioni con stratificazione in base alla presentazione clinica, ai reperti istopatologici e radiologici e alla risposta alla terapia con corticosteroidi [1]. L’istiocitosi polmonare a cellule di Langerhans (ICL) è un sottogruppo di patologia… 



Polyclonal T-Cells Express CD1a in Langerhans Cell Histiocytosis (LCH) Lesions

Using eight-colour flow cytometry, a previously unreported population of CD1a+/CD3+ T-cells in LCH lesions is identified, establishing thatCD1a expression in these lesions is no longer restricted to pathogenic LCs.

Adult pulmonary Langerhans’ cell histiocytosis

  • A. Tazi
  • Medicine
    European Respiratory Journal
  • 2006
Improved understanding of the mechanisms involved in the pathogenesis of pulmonary Langerhans’ cell histiocytosis is urgently needed, and should help in the development of specific therapeutic strategies for patients with this orphan disease.

Rare lung diseases III: pulmonary Langerhans' cell histiocytosis.

The present review discusses the presenting features and relevant diagnostic testing and treatment options for PLCH in the context of a clinical case, and recommends clinicians to distinguish the adult and pediatric forms of the disease.

Utility of Bronchoscopy in Pulmonary Langerhans Cell Histiocytosis

It is concluded that bronchoscopic lung biopsy is useful in the diagnosis of PLCH and should be the initial method of obtaining diagnostic specimens.

Pulmonary Langerhans Cell Histiocytosis

A previously healthy 27-year-old female admitted to a local hospital with history of chest pain and shortness of breath for several days and ceased smoking thereafter was diagnosed with PLCH and remained asymptomatic 31 months after surgery.

An official American Thoracic Society clinical practice guideline: the clinical utility of bronchoalveolar lavage cellular analysis in interstitial lung disease.

Recommendations for the performance and processing of BAL, as well as the interpretation of BAL findings, were formulated by the committee and frequently provide useful information for the diagnostic evaluation of patients with suspected ILD.

[Diagnosis of interstitial lung diseases].

Pulmonary Langerhans ’ cell histiocyto

  • Clin Chest Med
  • 2004

Riv Ital Med Lab

  • Riv Ital Med Lab
  • 2016