Utilising polyphenols for the clinical management of Candida albicans biofilms.

  title={Utilising polyphenols for the clinical management of Candida albicans biofilms.},
  author={Muhammad Tahir Shahzad and Leighann Sherry and Ranjith Kumar Rajendran and Christine Ann Edwards and Emilie Combet and Gordon Ramage},
  journal={International journal of antimicrobial agents},
  volume={44 3},
Polyphenols (PPs) are secondary metabolites abundant in plant-derived foods. They are reported to exhibit antimicrobial activity that may offer an alternative to existing antimicrobials. The aim of this study was to evaluate the antifungal potential of PPs against Candida albicans biofilms that are commonly recalcitrant to antifungal therapy. The antifungal activity of 14 PPs was assessed in terms of planktonic and sessile minimum inhibitory concentrations (PMICs and SMICs, respectively… CONTINUE READING
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