Uterine leiomyomas express a molecular pattern that lowers retinoic acid exposure.

@article{Catherino2007UterineLE,
  title={Uterine leiomyomas express a molecular pattern that lowers retinoic acid exposure.},
  author={William H Catherino and Minnie Malik},
  journal={Fertility and sterility},
  year={2007},
  volume={87 6},
  pages={1388-98}
}
OBJECTIVE To analyze expression of the retinoic acid signaling pathway genes that are involved in retinol metabolism, transport, transcriptional activation, and transcriptional products in spontaneous human leiomyomas. DESIGN Laboratory study of human leiomyoma and patient-matched myometrial tissue. PATIENT(S) Eight women undergoing hysterectomy for symptomatic leiomyomas. INTERVENTION(S) Confirmation of an altered retinoic acid pathway analyzed by microarray, real time reverse… CONTINUE READING