Uterine allotransplantation in ewes using an aortocava patch.

  title={Uterine allotransplantation in ewes using an aortocava patch.},
  author={Tristan Gauthier and François Bertin and Laurent M Fourcade and Antoine J. Maubon and Franck Saint Marcoux and Pascal Piver and Pierre Marquet and Isabelle Pommepuy and Xavier Plainard and Claude Couquet and M J Cornuejols and Marie Essig and Yves Aubard},
  journal={Human reproduction},
  volume={26 11},
BACKGROUND We investigated a novel allotransplantation model using an aortocava patch in ewes. METHODS AND RESULTS We carried out 10 uterine orthotopic allotransplantations in ewes with end-to-side anastomosis of the aortocava donor patch on the left external iliac vessel recipient. The immunosuppressive protocol was a combination of cyclosporine (10 mg/kg/day) and mycophenolic acid (3 g/day). An estimation of the immunosuppressive therapy exposure was performed by measuring the area under… CONTINUE READING


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