Ustilago maydis produces itaconic acid via the unusual intermediate trans‐aconitate

@inproceedings{Geiser2016UstilagoM,
  title={
Ustilago maydis produces itaconic acid via the unusual intermediate trans‐aconitate},
  author={Elena Geiser and Sandra K Przybilla and Alexandra Friedrich and Wolfgang Buckel and Nick J. P. Wierckx and Lars Mathias Blank and Michael B{\"o}lker},
  booktitle={Microbial biotechnology},
  year={2016}
}
Itaconic acid is an important biomass-derived chemical building block but has also recently been identified as a metabolite produced in mammals, which has antimicrobial activity. The biosynthetic pathway of itaconic acid has been elucidated in the ascomycetous fungus Aspergillus terreus and in human macrophages. In both organisms itaconic acid is generated by decarboxylation of the tricarboxylic acid (TCA) cycle intermediate cis-aconitate. Here, we show that the basidiomycetous fungus Ustilago… CONTINUE READING

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Itaconic acid production in microorganisms

Biotechnology Letters • 2017
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