Using whole-genome transcriptional analyses to identify molecular mechanisms of aging

@inproceedings{Murphy2006UsingWT,
  title={Using whole-genome transcriptional analyses to identify molecular mechanisms of aging},
  author={Coleen T. Murphy},
  year={2006}
}
Whole-genome transcriptional analyses of aging organisms and tissues have revealed changes in many genes and biological processes. A comparison of these studies reveals common age-related changes, including the downregulation of metabolic and mitochondrial function, and the upregulation of stress and immune responses. This suggests that much of the aging process might be conserved across species, although tissueand species-specific changes also occur. These comparisons will help identify the… CONTINUE READING
BETA

From This Paper

Figures, tables, and topics from this paper.

Explore Further: Topics Discussed in This Paper

References

Publications referenced by this paper.
SHOWING 1-10 OF 56 REFERENCES

A comparison of the aging and apoptotic transcriptome of Saccharomyces cerevisiae

  • P Laun
  • FEMS Yeast Res
  • 2005

Identification of a molecular signature of sarcopenia

  • Giresi, P.G
  • Physiol. Genomics
  • 2005

Similar Papers

Loading similar papers…