Using voxel-based morphometry to map the structural changes associated with rapid conversion in MCI: A longitudinal MRI study

@article{Chtelat2005UsingVM,
  title={Using voxel-based morphometry to map the structural changes associated with rapid conversion in MCI: A longitudinal MRI study},
  author={Ga{\"e}l Ch{\'e}telat and Brigitte Landeau and Francis Eustache and Florence M{\'e}zenge and Fausto Viader and Vincent de La Sayette and B{\'e}atrice Desgranges and J. C. Baron},
  journal={NeuroImage},
  year={2005},
  volume={27},
  pages={934-946}
}
Capturing the dynamics of gray matter (GM) atrophy in relation to the conversion from mild cognitive impairment (MCI) to clinically probable Alzheimer's disease (AD) would be of considerable interest. In this prospective study we have used a novel longitudinal voxel-based method to map the progression of GM loss in MCI patients over time and compared converters to non-converters. Eighteen amnestic MCI patients were followed-up for a predefined fixed period of 18 months and conversion was judged… Expand
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