Using traveling salesman problem algorithms for evolutionary tree construction

@article{Korostensky2000UsingTS,
  title={Using traveling salesman problem algorithms for evolutionary tree construction},
  author={Chantal Korostensky and Gaston H. Gonnet},
  journal={Bioinformatics},
  year={2000},
  volume={16 7},
  pages={619-27}
}
MOTIVATION The construction of evolutionary trees is one of the major problems in computational biology, mainly due to its complexity. RESULTS We present a new tree construction method that constructs a tree with minimum score for a given set of sequences, where the score is the amount of evolution measured in PAM distances. To do this, the problem of tree construction is reduced to the Traveling Salesman Problem (TSP). The input for the TSP algorithm are the pairwise distances of the… CONTINUE READING
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