Using the T-Coffee package to build multiple sequence alignments of protein, RNA, DNA sequences and 3D structures

@article{Taly2011UsingTT,
  title={Using the T-Coffee package to build multiple sequence alignments of protein, RNA, DNA sequences and 3D structures},
  author={Jean-François Taly and Cedrik Magis and Giovanni Bussotti and Jia-Ming Chang and Paolo Di Tommaso and Ionas Erb and Jose Espinosa-Carrasco and Carsten Kemena and C{\'e}dric Notredame},
  journal={Nature Protocols},
  year={2011},
  volume={6},
  pages={1669-1682}
}
T-Coffee (Tree-based consistency objective function for alignment evaluation) is a versatile multiple sequence alignment (MSA) method suitable for aligning most types of biological sequences. The main strength of T-Coffee is its ability to combine third party aligners and to integrate structural (or homology) information when building MSAs. The series of protocols presented here show how the package can be used to multiply align proteins, RNA and DNA sequences. The protein section shows how… CONTINUE READING
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