Using the Single Prolonged Stress Model to Examine the Pathophysiology of PTSD

@article{Souza2017UsingTS,
  title={Using the Single Prolonged Stress Model to Examine the Pathophysiology of PTSD},
  author={R. R. Souza and L. Noble and C. McIntyre},
  journal={Frontiers in Pharmacology},
  year={2017},
  volume={8}
}
The endurance of memories of emotionally arousing events serves the adaptive role of minimizing future exposure to danger and reinforcing rewarding behaviors. However, following a traumatic event, a subset of individuals suffers from persistent pathological symptoms such as those seen in posttraumatic stress disorder (PTSD). Despite the availability of pharmacological treatments and evidence-based cognitive behavioral therapy, a considerable number of PTSD patients do not respond to the… Expand
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