Using the Neurofibromatosis Tumor Predisposition Syndromes to Understand Normal Nervous System Development

@inproceedings{Garcia2014UsingTN,
  title={Using the Neurofibromatosis Tumor Predisposition Syndromes to Understand Normal Nervous System Development},
  author={Cynthia Garcia and David H Gutmann},
  booktitle={Scientifica},
  year={2014}
}
Development is a tightly regulated process that involves stem cell self-renewal, differentiation, cell-to-cell communication, apoptosis, and blood vessel formation. These coordinated processes ensure that tissues maintain a size and architecture that is appropriate for normal tissue function. As such, tumors arise when cells acquire genetic mutations thatā€¦Ā CONTINUE READING