Using the Internal Stress Concept to Assess the Importance of Moisture Sorption-induced Swelling on the Moisture Transport through the Glassy HPMC Films

@article{Laksmana2008UsingTI,
  title={Using the Internal Stress Concept to Assess the Importance of Moisture Sorption-induced Swelling on the Moisture Transport through the Glassy HPMC Films},
  author={Fesia Lestari Laksmana and Paul J. A. Hartman Kok and Henderik W. Frijlink and Herman Vromans and Kees Voort Maarschalk},
  journal={AAPS PharmSciTech},
  year={2008},
  volume={9},
  pages={891-898}
}
The purpose of this research was to elucidate the significance of the changes in the mechanical and the volumetric properties on the moisture diffusivity through the polymer films. The internal stress concept was adapted and applied to estimate the relative impact of these property changes on the total stress experienced by a polymer film during storage. Hydroxypropyl Methylcellulose free films were used as a model material prepared at various conditions and stored at different relative… 
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