Using the COG Database to Improve Gene Recognition in Complete Genomes

@article{Natale2000UsingTC,
  title={Using the COG Database to Improve Gene Recognition in Complete Genomes},
  author={Darren A. Natale and Michael Y. Galperin and Roman L. Tatusov and Eugene V. Koonin},
  journal={Genetica},
  year={2000},
  volume={108},
  pages={9-17}
}
A complete understanding of the biology of an organism necessarily starts with knowledge of its genetic makeup. Proteins encoded in a genome must be identified and characterized, and the presence or absence of specific sets of proteins must be noted in order to determine the possible biochemical pathways or functional systems utilized by that organism. The COG database presents a set of tools suited to these purposes, including the ability to select protein families (COGs) that contain proteins… CONTINUE READING
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