Using the CATH domain database to assign structures and functions to the genome sequences.

@article{Pearl2000UsingTC,
  title={Using the CATH domain database to assign structures and functions to the genome sequences.},
  author={Frances M. G. Pearl and Annabel E. Todd and James E. Bray and A. C. Martin and Asaf A. Salamov and Makiko Suwa and Mark B. Swindells and Janet M. Thornton and Christine A. Orengo},
  journal={Biochemical Society transactions},
  year={2000},
  volume={28 2},
  pages={269-75}
}
The CATH database of protein structures contains approximately 18000 domains organized according to their (C)lass, (A)rchitecture, (T)opology and (H)omologous superfamily. Relationships between evolutionary related structures (homologues) within the database have been used to test the sensitivity of various sequence search methods in order to identify… CONTINUE READING