Using systematic reviews to inform NIHR HTA trial planning and design: a retrospective cohort.

@article{Bhurke2015UsingSR,
  title={Using systematic reviews to inform NIHR HTA trial planning and design: a retrospective cohort.},
  author={Sheetal Bhurke and Andrew Cook and Anna Tallant and Amanda J. Young and E Dillwyn Williams and James Raftery},
  journal={BMC medical research methodology},
  year={2015},
  volume={15},
  pages={108}
}
BACKGROUND Chalmers and Glasziou's paper published in 2014 recommends research funding bodies should mandate that proposals for additional primary research are built on systematic reviews of existing evidence showing what is already known. Jones et al. identified 11 (23%) of 48 trials funded during 2006-8 by the National Institute for Health Research Health Technology Assessment (NIHR HTA) Programme did not reference a systematic review. This study did not explore the reasons for trials not… CONTINUE READING
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Many reports of randomised trials still don’t begin or end with a systematic review of the relevant evidence

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