Using short-term response information to facilitate adaptive randomization for survival clinical trials.

Abstract

Increased survival is a common goal of cancer clinical trials. Owing to the long periods of observation and follow-up to assess patient survival outcome, it is difficult to use outcome-adaptive randomization in these trials. In practice, often information about a short-term response is quickly available during or shortly after treatment, and this short-term… (More)
DOI: 10.1002/sim.3578

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Cite this paper

@article{Huang2009UsingSR, title={Using short-term response information to facilitate adaptive randomization for survival clinical trials.}, author={Xuelin Huang and Jing Ning and Yisheng Li and Elihu Estey and Jean-Pierre Issa and Donald A. Berry}, journal={Statistics in medicine}, year={2009}, volume={28 12}, pages={1680-9} }