Using scattering and absorption spectra as MCR-hard model constraints for diffuse reflectance measurements of tablets.

@article{Kessler2009UsingSA,
  title={Using scattering and absorption spectra as MCR-hard model constraints for diffuse reflectance measurements of tablets.},
  author={Waltraud Kessler and Dieter Oelkrug and R. W. Kessler},
  journal={Analytica chimica acta},
  year={2009},
  volume={642 1-2},
  pages={127-34}
}
One of the most often used tools in process analytical technology (PAT) is NIR spectroscopy as a non-destructive fast and reliable method to identify and quantify active pharmaceutical ingredients (API) in tablets. Very little work has been devoted to analyse the effects of scatter on quantitative analysis of the chemical composition. A novel approach to… CONTINUE READING