Using pulmonary imaging to move chronic obstructive pulmonary disease beyond FEV1.

@article{Coxson2014UsingPI,
  title={Using pulmonary imaging to move chronic obstructive pulmonary disease beyond FEV1.},
  author={Harvey O Coxson and Jonathan Avrom Leipsic and Grace Parraga and Don D. Sin},
  journal={American journal of respiratory and critical care medicine},
  year={2014},
  volume={190 2},
  pages={135-44}
}
FEV1, measured using spirometry, provides a straightforward, widely available, and inexpensive global measurement of airflow limitation and lung function. For decades, FEV1 has remained the main intermediate endpoint used in research studies and for the development of new chronic obstructive pulmonary disease (COPD) therapies. Not surprisingly, treatments that acutely improve FEV1 dominate as COPD therapies. However, in patients with COPD, the relationship of FEV1 with symptoms and outcomes… CONTINUE READING
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