Using positron emission tomography 2-deoxy-2-[18F]fluoro-D-glucose, 11CO, and 15O-water for monitoring androgen independent prostate cancer.

@article{Kurdziel2003UsingPE,
  title={Using positron emission tomography 2-deoxy-2-[18F]fluoro-D-glucose, 11CO, and 15O-water for monitoring androgen independent prostate cancer.},
  author={Karen A. Kurdziel and William D. Figg and Jorge A. Carrasquillo and Susan Huebsch and Millie Whatley and David Sellers and Steven K. Libutti and James M. Pluda and William D. Dahut and Edward P. Reed and Stephen L. Bacharach},
  journal={Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging},
  year={2003},
  volume={5 2},
  pages={86-93}
}
PURPOSE Monitoring of androgen independent prostate cancer (AIPC) therapy involves monitoring prostate specific antigen (PSA) blood serum concentrations; however, the reliability of small changes in PSA values has been questioned. We performed a small pilot study to determine whether PET might be a useful monitor of changes during anti-angiogenic therapy in AIPC. PROCEDURES Changes in tumor blood flow ([15O] water), blood volume ([11C]CO), 2-deoxy-2-[18F]fluoro-D-glucose (FDG) uptake and… CONTINUE READING