Using physicochemical properties of amino acids to induce graphical models of residue couplings

Abstract

Residue coupling in protein families is an important indicator for structural and functional conservation. Two residues are coupled if changes of amino acid at one residue location are correlated with changes in the other. Many algorithmic techniques have been proposed to discover couplings in protein families. These approaches discover couplings over amino… (More)
DOI: 10.1145/2003351.2003354

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