Using nonrandom two-liquid model for solvent system selection in counter-current chromatography.

Abstract

Selection of an appropriate solvent system is of great importance for a successful counter-current chromatography separation. In this work, the nonrandom two-liquid (NRTL) model, a thermodynamic method, was used for predicting the partition coefficient based on a few measured partition coefficients. The NRTL method provides quite satisfactory results for… (More)
DOI: 10.1016/j.chroma.2014.05.080

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