Using models of nucleotide evolution to build phylogenetic trees.

  title={Using models of nucleotide evolution to build phylogenetic trees.},
  author={David H. Bos and David Posada},
  journal={Developmental and comparative immunology},
  volume={29 3},
Molecular phylogenetics and its applications are popular and useful tools for making comparative investigations in genetics; however, estimating phylogenetic trees is not always straightforward. Some phylogenetic estimators use an explicit model of nucleotide evolution to estimate evolutionary parameters such as branch lengths and tree topology. There are many models to choose from, and use of the optimal model for a particular data set is important to avoid a loss of power and accuracy in… CONTINUE READING
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