Using modafinil to treat fatigue in Parkinson disease: a double-blind, placebo-controlled pilot study.

@article{Lou2009UsingMT,
  title={Using modafinil to treat fatigue in Parkinson disease: a double-blind, placebo-controlled pilot study.},
  author={J S Lou and Diana M. Dimitrova and Byung Sam Park and Sarah C Johnson and Ryan W. Eaton and Grace Arnold and John G. Nutt},
  journal={Clinical neuropharmacology},
  year={2009},
  volume={32 6},
  pages={305-10}
}
BACKGROUND Fatigue is a major nonmotor symptom in Parkinson disease(PD). It is associated with reduced activity and lower quality of life. OBJECTIVE To determine if modafinil improves subjective fatigue and physical fatigability in PD. METHODS Nineteen PD patients who reported significant fatigue in the Multidimensional Fatigue Inventory (MFI) participated in this 8-week study. Subjects took their regular medications and were randomly assigned to the treatment group (9 subjects, modafinil… CONTINUE READING
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