Using metabotropic glutamate receptors to modulate cocaine's synaptic and behavioral effects: mGluR1 finds a niche.

@article{Loweth2013UsingMG,
  title={Using metabotropic glutamate receptors to modulate cocaine's synaptic and behavioral effects: mGluR1 finds a niche.},
  author={Jessica A. Loweth and Kuei Yuan Tseng and Marina E Wolf},
  journal={Current opinion in neurobiology},
  year={2013},
  volume={23 4},
  pages={500-6}
}
Group I metabotropic glutamate receptors (mGluR) are important modulators of excitatory synaptic transmission and therefore potential targets for drug development. In several brain regions (ventral tegmental area (VTA), cerebellum, and amygdala), stimulation of mGluR1 selectively inhibits synaptic transmission mediated by calcium-permeable AMPA receptors… CONTINUE READING