Using liquid crystals as a readout system in urinary albumin assays.

@article{Alio2011UsingLC,
  title={Using liquid crystals as a readout system in urinary albumin assays.},
  author={Vera Joanne Ali{\~n}o and Kun-Lin Yang},
  journal={The Analyst},
  year={2011},
  volume={136 16},
  pages={
          3307-13
        }
}
Detecting human serum albumin (HSA) in urine samples is a standard procedure for the diagnosis of kidney problems and the prognosis of patients with chronic kidney diseases (CKDs). In this study, we developed a HSA assay by incorporating a thin layer of liquid crystals (LCs) as a readout system such that the presence of HSA in urine samples can be detected as optical signals. In combination with dilution protocols, this assay can be used to estimate the concentration range of HSA simply by… Expand
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Liquid crystal-based immunoassay for detecting human serum albumin
Human serum albumin (HSA) is the most abundant protein in human blood plasma. It is commonly used as a biomarker in urine samples to identify the chronic kidney disease caused by high blood pressure… Expand
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This paper presents a wireless immunoglobulin-coated magnetoelastic (ME) biosensor for fast, cost-effective detections of human serum albumin (HSA) with small sample volumes at a microliter scale and shows high potential to be used in diagnosing abnormal HSA. Expand
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A novel single-site, double-sensing fluorescent probe 1 is reported, based on the finding that HSA can catalyze a Michael addition reaction between the probe and SO2, which induces a change in fluorescence, which may provide a significant boost in the study of the role of HSA in medicine and pharmacy. Expand
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TLDR
A novel hydrazide Schiff base fluorescent probe N'-((7-(diethylamino)-2-oxo-2H-chromen-3-yl)methylene)pyrazine-2-carbohydrazide (NPC), which self-assembled into nanoparticles in aqueous solution, which exhibited superior selectivity and sensitivity toward HSA. Expand
Red-emitting benzo[e]indolium probes for HSA based on the TICT characteristics
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