Using known drug interactions to manage supratherapeutic calcineurin inhibitor concentrations.

Abstract

OBJECTIVES To summarize the available body of evidence guiding the management of supratherapeutic concentrations of calcineurin inhibitors (CNI) using cytochrome P450 (CYP450) enzyme inducers. METHODS A nondate restricted literature search within MEDLINE, Embase, and Scopus was performed using the terms "cyclosporine," "tacrolimus," "calcineurin inhibitor… (More)
DOI: 10.1111/ctr.13098

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