Using hexamers to predict cis-regulatory motifs in Drosophila

  title={Using hexamers to predict cis-regulatory motifs in Drosophila},
  author={Bob Y. Chan and Dennis F. Kibler},
  journal={BMC Bioinformatics},
  pages={262 - 262}
Cis-regulatory modules (CRMs) are short stretches of DNA that help regulate gene expression in higher eukaryotes. They have been found up to 1 megabase away from the genes they regulate and can be located upstream, downstream, and even within their target genes. Due to the difficulty of finding CRMs using biological and computational techniques, even well-studied regulatory systems may contain CRMs that have not yet been discovered. We present a simple, efficient method (HexDiff) based only on… CONTINUE READING
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