Using helium-oxygen to improve regional deposition of inhaled particles: mechanical principles.

@article{Katz2014UsingHT,
  title={Using helium-oxygen to improve regional deposition of inhaled particles: mechanical principles.},
  author={Ira Katz and Marine Pichelin and Spyridon Montesantos and Caroline Majoral and Alain Martin and Joy Conway and Jonathan Paul Fleming and Jose Gabriel Venegas and Elliot Eliyahu Greenblatt and George Caillibotte},
  journal={Journal of aerosol medicine and pulmonary drug delivery},
  year={2014},
  volume={27 2},
  pages={
          71-80
        }
}
BACKGROUND Helium-oxygen has been used for decades as a respiratory therapy conjointly with aerosols. It has also been shown under some conditions to be a means to provide more peripheral, deeper, particle deposition for inhalation therapies. Furthermore, we can also consider deposition along parallel paths that are quite different, especially in a heterogeneous pathological lung. It is in this context that it is hypothesized that helium-oxygen can improve regional deposition, leading to more… CONTINUE READING
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