Using growth models to relate acquisition of nicotine self-administration to break point and nicotinic receptor binding.

@article{Donny2004UsingGM,
  title={Using growth models to relate acquisition of nicotine self-administration to break point and nicotinic receptor binding.},
  author={Eric C. Donny and Stephanie T. Lanza and Robert L. Balster and Linda M. Collins and Anthony Caggiula and Peter P. Rowell},
  journal={Drug and alcohol dependence},
  year={2004},
  volume={75 1},
  pages={23-35}
}
Growth modeling can be used to characterize individual and mean acquisition trajectories for drug self-administration. Individual characteristics can also be incorporated into the growth model, providing a powerful tool for investigating the relationship between acquisition and other behavioral and biological measures. We illustrate the utility of this method by examining the relationship between acquisition of nicotine self-administration and (1) break point on a progressive ratio schedule of… CONTINUE READING