Using growth factor arrays and micropatterned co-cultures to induce hepatic differentiation of embryonic stem cells.


The success in driving embryonic stem cells towards hepatic lineage has been confounded by the complexity and cost of differentiation protocols that employ large quantities of expensive growth factors (GFs). Instead of supplementing culture media with soluble GFs, we investigated cultivation and differentiation of mouse embryonic stem cells (mESCs) on… (More)
DOI: 10.1016/j.biomaterials.2010.08.050


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