Using graphical displays of exact overall significance levels as a guideline for choosing a significance level for pairwise comparisons of a dichotomous variable.


Exact overall significance levels for selected sample sizes and response probabilities are graphically displayed when a dichotomous variable is compared between a placebo and two or more active treatments. A Z-statistic with a pooled variance estimator is used as the test statistic and critical values are based on the (1 - alpha/2)th percentile of the… (More)