Using ensemble methods to deal with imbalanced data in predicting protein-protein interactions

Abstract

In proteins, the number of interacting pairs is usually much smaller than the number of non-interacting ones. So the imbalanced data problem will arise in the field of protein-protein interactions (PPIs) prediction. In this article, we introduce two ensemble methods to solve the imbalanced data problem. These ensemble methods combine the based-cluster under… (More)
DOI: 10.1016/j.compbiolchem.2011.12.003

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