Using dynamic sensitivities to characterize metabolic reaction systems.


Metabolite concentrations in cells are governed by enzyme kinetics in the metabolic reaction system. One can analyze how these concentrations depend on system variables such as enzyme activities by computing system sensitivities, which generally vary with time. Dynamic sensitivities, i.e., time-varying sensitivities, reflect the time-dependent response of… (More)
DOI: 10.1016/j.mbs.2015.09.002


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