Using computer simulations to determine the limitations of dynamic clamp stimuli applied at the soma in mimicking distributed conductance sources.

@article{Lin2011UsingCS,
  title={Using computer simulations to determine the limitations of dynamic clamp stimuli applied at the soma in mimicking distributed conductance sources.},
  author={Risa J. Lin and Dieter Jaeger},
  journal={Journal of neurophysiology},
  year={2011},
  volume={105 5},
  pages={
          2610-24
        }
}
  • R. Lin, D. Jaeger
  • Published 16 February 2011
  • Biology
  • Journal of neurophysiology
In previous studies we used the technique of dynamic clamp to study how temporal modulation of inhibitory and excitatory inputs control the frequency and precise timing of spikes in neurons of the deep cerebellar nuclei (DCN). Although this technique is now widely used, it is limited to interpreting conductance inputs as being location independent; i.e., all inputs that are biologically distributed across the dendritic tree are applied to the soma. We used computer simulations of a… 

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